Description
Hair Loss Treatment Pyramid
The order matters more than the number of treatments. Most people start by chasing growth. A smarter strategy starts by protecting what you still have—then adds only what your situation requires
https://letsgethair.com/hair-loss-treatment-pyramid/
1:1 Consultation — for anything hair loss and hair transplant related
https://letsgethair.com/schedule-consultation/
Studies & Sources Referenced:
1. Umar S, Tan BH, Shitabata PK. “Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment — A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp.” Clinical, Cosmetic and Investigational Dermatology. 2026;19:1–16. DOI: 10.2147/CCID.S548520
(The 129-patient “PIILIF” study — proposes DHT upstream of fibrosis, not the reverse)
2. Yoo HG, Kim JS, Lee SR, et al. “Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia.” Biological and Pharmaceutical Bulletin. 2006;29(6):1246–1250. DOI: 10.1248/bpb.29.1246
3. Sawaya ME, Price VH. “Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia.” Journal of Investigative Dermatology. 1997;109(3):296–300. DOI: 10.1111/1523-1747.ep12335779
4. Sánchez P, Serrano Falcón C, Martínez Rodríguez S, Torres JM, Serrano S, Ortega E. “mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia.” International Journal of Molecular Sciences. 2023;24(24):17461. DOI: 10.3390/ijms242417461
5. Randall VA, Thornton MJ, Messenger AG. “Cultured Dermal Papilla Cells from Androgen-Dependent Human Hair Follicles (e.g. Beard) Contain More Androgen Receptors Than Those from Non-Balding Areas of Scalp.” Journal of Endocrinology. 1992;133(1):141–147.
6. Hibberts NA, Howell AE, Randall VA. “Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those from Non-Balding Scalp.” Journal of Endocrinology. 1998;156(1):59–65. PMID: 9496234
7. Inui S, Fukuzato Y, Nakajima T, et al. “Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth.” FASEB Journal. 2002;16(14):1967–1969. DOI: 10.1096/fj.02-0043fje
8. Panchaprateep R, Asawanonda P. “Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia.” Experimental Dermatology. 2014;23(3):216–218. DOI: 10.1111/exd.12339
9. Melo CSB, et al. “Efficacy of Botulinum Toxin in Male Androgenetic Alopecia: A Triple-Blind, Randomized Clinical Trial.” Journal of the American Academy of Dermatology. 2024. DOI: 10.1016/j.jaad.2024.07.1464
10. Koyama T, Kobayashi K, Hama T, Murakami K, Ogawa R. “Standardized Scalp Massage Results in Increased Hair Thickness by Inducing Stretching Forces to Dermal Papilla Cells in the Subcutaneous Tissue.” Eplasty. 2016;16:e8. PMID: 26904154
11. Vosoughi S, Roy D, Aral S. “The Spread of True and False News Online.” Science. 2018;359(6380):1146–1151. DOI: 10.1126/science.aap9559